Poster F54, Tuesday, March 27, 8:00-10:00 am, Exhibit Hall C
Baseline semantic processing skills are important for typicality-based naming therapy outcomes
Natalie Gilmore1, Erin Meier1, Jeffrey P. Johnson1, Swathi Kiran1; 1Boston University
Goal: To examine the degree to which semantic and/or phonologic deficit profiles predict treatment response from typicality-based semantic feature analysis (SFA) treatment in persons with aphasia (PWA). Methods: Twenty-seven PWA underwent SFA to improve word retrieval post-stroke. Baseline assessments were given to assess specific aspects of the lexical retrieval process: Pyramids and Palm Trees Test (nonverbal semantics), semantic feature and category verification tasks (lexical-semantics), phonological processing tasks requiring lexical retrieval (phonological output lexicon), and phonological tasks involving rhyme judgment, phoneme verification, and nonword discrimination (phonological buffer). After therapy, proportion of potential maximal gain (PMG) from treatment was calculated. Baseline scores on the language assessment measures were entered into independent linear regressions predicting PMG. Results: The model including nonverbal semantic processing, treatment response, and their interaction explained 85% of the variance in PMG (F (4, 22) = 31.14, p < .001). Controlling for aphasia severity, the interaction term was significant (β = 2.70, p = .002), indicating that PWA who responded positively to treatment had higher pre-treatment amodal semantic processing ability, and that this finding was not driven by overall language impairment. Furthermore, the integrity of lexical-semantic processing, the phonological output lexicon, and the phonological buffer system at baseline did not significantly predict outcomes of typicality-based SFA treatment. Conclusion: Heterogeneity in semantic treatment response may be in part explained by pre-treatment nonverbal semantic processing ability. These results suggest that PWA, who responded favorably to this treatment approach, relied on their intact semantic system to strengthen their lexical retrieval skills.
Topic Area: LANGUAGE: Semantic