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Poster E74

Introducing the Mini-Intraoperative Language Test (MILT): a new language battery for awake brain surgeries

Poster Session E - Monday, April 15, 2024, 2:30 – 4:30 pm EDT, Sheraton Hall ABC

Giovanna Oliveira Santos1 (, Analia Arevalo1, Marije Soto2, Márcia Otsubo, Juliana Novo Gomes3, Sônia Lopes, Aniela Improta França2, Vitoria Piai4, Guilherme Lepski1,5; 1University of São Paulo Medical School, 2Federal University of Rio de Janeiro, 3University of Porto, 4Radboud University, 5Eberhard Karls University

Intraoperative awake language mapping is currently the state-of-the-art method to assess language organization and prevent postoperative deficits. Besides its clinical applications, this technique can significantly contribute to our understanding of cortical language organization within and across individuals. However, there is currently no standard protocol used across centers. Here we present a new language battery created in Brazil, the Mini-Intraoperative Language Test (MILT), which contains 10 language subtests that can be applied in 3- to 5-minute time windows and repeated (in different versions) across 10-15 pre-mapped cortical sites. We apply the Tanigushi method, which uses monopolar electrodes to induce stimulation for longer periods of time (3-5 minutes vs. 4 seconds, as in the Penfield method), and can reduce the incidence of epileptic seizures. Here we present the subtests, the normative studies conducted in Brazilian Portuguese to create them, and data from two pilot cases. In the future, our aim is to adapt MILT to different languages and develop an automated platform that makes MILT application and analysis in the surgical environment more efficient.

Topic Area: METHODS: Other


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April 13–16  |  2024