Poster E75, Monday, March 26, 2:30-4:30 pm, Exhibit Hall C
Investigating the Neural Bases of Featured-Based Semantic Control: Evidence from High Resolution Functional Neuroimaging
Andrew C. Connolly1, Gavin K. Hanson2, Evangelia G. Chrysikou3; 1Dartmouth School of Medicine, 2Case Western Reserve, 3University of Kansas
Prior neuroimaging evidence using multivoxel pattern analyses has offered support for a domain-general system that is active in shifting attention toward concrete (e.g. color, shape) and abstract (e.g. function, thematic context) features during goal-directed object knowledge retrieval (Hanson & Chrysikou, 2017). However, precisely how these semantic features, as well as their conjunctions, are represented within this hypothesized attentional system remains unexplored. Here, we employed a high-resolution functional magnetic resonance imaging (fMRI) protocol with the goal of identifying feature-selective attentional signals that would support some domain specificity according to a particular topographical organization within frontal and parietal cortex. Healthy adult participants performed a semantic decision making task according to which they matched a cue word to one of three targets depending on a single feature (i.e., color, shape, function) or a conjunction of features (i.e., color and shape; color and function; shape and function). Univariate model-based and multivoxel pattern analyses revealed the contributions of frontotemporal and dorsoparietal networks in guiding attention to goal-oriented features and their conjunctions during semantic control. We discuss how these results support a frontoparietal network of regions guiding attention to different concrete and abstract semantic properties during flexible, goal-oriented object knowledge retrieval.
Topic Area: LONG-TERM MEMORY: Semantic