Poster F13, Tuesday, March 27, 8:00-10:00 am, Exhibit Hall C
Neurocognitive and emotion processing deficits in Bipolar Disorder and their first degree relatives
Hugo Sandoval1, Jose Gavito1, Christopher Dodoo2, Michael Escamilla3; 1Texas Tech PLFSOM El Paso Radiology, 2Texas Tech PLFSOM El Paso Biostatistics and Epidemiology, 3Texas Tech PLFSOM El Paso Psychiatry
Specific Goals The objective of this study is to characterize nerucogntive and emotion processing deficits in Bipolar disorder type I (BPI) patients and children and adolescents at risk for BPI. This information can be used to give this patients tools to prevent worsening of the illness or to provide early treatment, . Methods Neurocognitive evaluation was performed on kids and adolescents with BPI, at risk for BPI, and healthy controls using the South Texas Assessment of Neurocognition (STAN). All diagnosis was conducted by a team of psychologists and psychiatrists to assign final consensus diagnoses using DSM-IV criteria. Multivariate linear regression was adjusted for age, gender, language spoken at home and race. P values less than 5% were considered statistically significant. All analysis were performed using SAS 9.4. Results summary Emotional judgment, sensory/motor processing speed, attention, executive function, and risk judgment were affected (P<0.05) )in children and adolescents at risk for BPI. Global/intellectual functioning, language skills, sensory/motor processing speed, attention, memory, language skills, and risk judgment were impaired in BPI children and adolescents. Conclusion. Our results provide evidence of neurocognitive and emotional impairment in kids and adolescents with BPI and in kids and adolescents at risk of developing BPI because of having a first degree relative with BPI. These deficits, add burden and complexity to the life of those who suffer from BPI or have a first degree relative who suffers from it. This information can be useful in developing neurocognitive therapy as well as educational alternatives for those in need.
Topic Area: EMOTION & SOCIAL: Emotion-cognition interactions