Poster A80, Saturday, March 24, 1:30–3:30 pm, Exhibit Hall C
P300 and theta-band oscillation: two expressions of a single novelty response
Xueyan Niu1, Guang Ouyang1, Yunqing Hua1, Akaysha Tang1; 1The Laboratory of Neuroscience for Education, Faculty of Education, The University of Hong Kong
Theta band oscillatory activity and P300 component in event-related potentials are both associated with novelty-related processing typically studied under separate experimental paradigms. The relation between these two forms of neural signatures of novelty has only been explored using scalp recorded EEG data at a few selected electrodes locations and no reference to the underlying neural generators was made in this context. The present work is built upon the study presented by Ouyang et al (submitted to CNS 2018, poster ID 713) where second order blind identification (SOBI) was used to recover neuronal sources, from high-density EEG (128 channels) data collected during a visual oddball task. Applying a Fourier transform to single-trial ERPs of the recovered P300 source, we explored the relation between the P300 and theta expressions of the novelty response to low versus high probability stimuli. We found that the low probability stimuli (50 trials) generated a significantly greater power, specifically in theta band (4-8Hz) activity, than did the high probability stimuli (200 trials) (one-tailed t(14) = 2.03, p = .03, effect size Cohen’s d = 0.52). This result demonstrated a direct relation between oddball induced P300 in the ERP and theta-band activity in a neuronal source consisting of a network of regions across frontal, temporal, and occipital lobes.
Topic Area: METHODS: Neuroimaging