Poster C26, Sunday, March 25, 1:00-3:00 pm, Exhibit Hall C
The relative neuropsychological effects of physical, cognitive, and interactive exercise (iPACES™) for mild cognitive impairment (MCI): Pilot data comparing two-week windows of each as in-home interventions
Kathryn M Wall1, Jessica Stark1, Alexa Schillaci1, Carolyn Doty1, Hannah Christian1, Anvit Karla-Lall1, Molly Maloney1, Cay Anderson-Hanley1; 1Union College, NY
Dementia cases are on the rise among our aging global population, and thus there is increasing urgency to identify efficacious interventions for preserving or ameliorating cognitive decline. Physical exercise has been found to slow the decline of cognitive abilities in those with mild cognitive impairment (MCI). Cognitive training has sometimes been reported to have a positive effect, but many critiques cast doubt on its ability to be widely endorsed as an effective treatment. Some research has found that interventions which combine both physical and cognitive exercise may yield greater benefits. This quasi-experimental within-subjects design compared each of these three components to assess impact on neuropsychological function. Participants were evaluated over eight weeks at two week intervals. Executive function was assessed at each evaluation through the use of tablet-based neuropsychological tests (i.e., Stroop, Trails and Flanker). The Montreal Cognitive Assessment (MoCA) was also used to assess overall cognitive function. This pilot study enrolled 14 older adults, 13 of which met criteria for MCI (MoCA< 26), with ten study completers. Paired t-tests were used to compare change from baseline to after each condition. Relative comparisons were also made between conditions. Results suggest that cognitive exercise (game-only) and interactive physical and cognitive exercise (iPACES™) yielded significant gains in executive function from baseline (moderate effect sizes), with the iPACES™ improving significantly more than exercise alone (p = .04). Further research is needed to replicate and extend this pilot research; in particular, it would be useful to compare such interventions in a randomized controlled trial.
Topic Area: EXECUTIVE PROCESSES: Development & aging