Poster B119, Sunday, March 25, 8:00-10:00 am, Exhibit Hall C
Effects of Multicomponent Training of Cognitive Control (MTCC) on Cognitive and Brain Structural Changes in Adolescents
Dasom Lee1, Seyul Kwak1, Jeanyung Chey1; 1Seoul National University
Cognitive control refers to the ability to adjust a series of thoughts and behaviors in correspondence to an internal goal. Adolescence is a unique period in which cognitive control ability develops to adult-level and neural and behavioral plasticities are high. However, there are limited numbers of cognitive training for adolescents and specific underlying mechanism of brain structure has not been established yet. This study was conducted to investigate the effects of Multicomponent Training of Cognitive Control (MTCC), whether the training enhanced adolescents' cognitive control ability and the effects were generalized to other cognitive domains. Participants were middle school students (aged 11-14) and they performed 30 minutes of MTCC per day for 6 weeks. For analysis, we examined the relationship between the changes in cognitive performance and regional gray matter volume using Voxel-based morphometry (VBM). We conducted small-volume correction (SVC) method to narrow the region of interest into the right inferior frontal cortex (rIFC) because rIFC is the critical area associated with inhibition. After the training, there were significant improvements in the block design test. Furthermore, VBM analysis showed that the volume of rIFC increased in the training group compared to the control group. Moreover, the increased volume of rIFC was correlated with better performances in the Stroop color-word reading, Stroop interference index, and delayed recall of verbal paired associates task. These results imply that MTCC has improved cognitive control ability in adolescents, especially the inhibition sub-component.
Topic Area: EXECUTIVE PROCESSES: Development & aging