Poster Session C, Sunday, March 24, 5:00 – 7:00 pm, Pacific Concourse
Verbal and Visual Memory in Metabolic Versus Control Participants Across the Adult Lifespan
Tracey Slonim1, Andres Fiello1, Lori Haase-Alasantro2, Claire Murphy1,2; 1San Diego State University, 2University of California, San Diego
Metabolic syndrome(MetS) is an established risk factor for developing dementia.Extant literature demonstrates a relationship between poor vascular health and decreases in cognitive functioning for older adults.This research will examine neuropsychological test performance in young, middle-aged, and older adults with and without MetS.Participants were categorized by age and metabolic status as follows:Young:n=42,52.4%Metabolic; Middle-Age:n=41,56.1%Metabolic; Older:n=45,51.1%Metabolic. Participants were administered the following cognitive assessments as part of a larger study:California Verbal Learning Test-II(CVLT-II) and Brief Visuospatial Memory Test-Revised(BVMT-R). Multivariate analyses of variance were used to examine the relationship between age group, metabolic status, and neuropsychological test performance. Bonferroni post-hoc analyses were used to determine significant differences on performance between age groups.As expected, there were main effects of age on all neuropsychological tests administered.The CVLT-II total list learning[F(1,111)=6.75,p=.002,eta-squared=.110], short delay free [F(1,111)=8.41,p<.001,eta-squared=.134], and cued recall [F(1,111)=6.03,p=.003,eta-squared=.100], and long delay free [F(1,111)=10.18,p<.001,eta-squared=.157],and cued recall performances[F(1,111)=5.93,p=.004,eta-squared=.098], were significantly different between age groups.The young adults performed significantly better than the older adults on the CVLT-II overall(p<.05).BVMT-R total learning [F(1,108)=10.94,p<.001,eta-squared=.171], and delayed recall[F(1,108)=5.35,p=.006,eta-squared=.092] performances were significantly different between age groups.Young adult performance was significantly higher on BVMT-R total learning compared to middle and older adult performances(p=.039 and p<.001, respectively).Young adults also scored significantly better on BVMT-R delayed recall compared with older adults(p=.004).There were no main effects of MetS, nor significant interactions between metabolic status and age group.Consistent with the current literature, memory decreases significantly in older adults.The sequelae of MetS may not manifest until later in life and may be overshadowed by the impact of aging on memory.
Topic Area: LONG-TERM MEMORY: Development & aging