Poster Session C, Sunday, March 24, 5:00 – 7:00 pm, Pacific Concourse
Neural Correlates of Familiarity in Music Listening: A Systematic Review and a Neuroimaging Meta-Analysis
Carina Freitas1,2, Enrica Manzato3, Alessandra Burini3, Margot J. Talyor1,4,5,6, Jason P. Lerch6,7,8, Evdokia Anagnostou1,2,6,9; 1Faculty of Medicine, Institute of Medical Science, University of Toronto, Toronto, ON, Canada, 2Bloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, Toronto, ON, Canada, 3Sant'Anna School of Advanced Studies, Pisa, Italy, 4Department of Diagnostic Imaging, Hospital for Sick Children, Toronto, ON, Canada, 5Department of Psychology, University of Toronto, Toronto, ON, Canada, 6Neuroscience & Mental Health Program, Hospital for Sick Children Research Institute, Toronto, ON, Canada, 7Mouse Imaging Centre, Hospital for Sick Children, Toronto, ON, Canada, 8Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada, 9Department of Pediatrics, University of Toronto, Toronto, ON, Canada
Familiarity in music has been reported as an important factor modulating emotional and hedonic responses in the brain. Familiarity and repetition may increase the liking of a piece of music, thus inducing positive emotions. Neuroimaging studies have focused on identifying the brain regions involved in the processing of familiar and unfamiliar musical stimuli. However, the use of different modalities and experimental designs has led to discrepant results and it is not clear which areas of the brain are most reliably engaged when listening to familiar and unfamiliar musical excerpts. In the present study, we conducted a systematic review from three databases (Medline, PsychoINFO, and Embase) using relevant keywords. Of the 704 titles identified, 23 neuroimaging studies met our inclusion criteria for the systematic review. After removing studies providing insufficient information or contrasts, 11 studies (involving 212 participants) qualified for the meta-analysis using the activation likelihood estimation (ALE) approach. Our results did not find significant peak activations consistently across included studies. Using a less conservative approach (p < 0.001, uncorrected for multiple comparisons) we found that the left superior frontal gyrus, the ventral lateral (VL) nucleus of the left thalamus, and the left medial surface of the superior frontal gyrus had the highest likelihood of being activated by familiar music. On the other hand, the left insula, and the right anterior cingulate cortex had the highest likelihood of being activated by unfamiliar music. Music familiarity had a motor pattern of activation which could reflect an audio-motor synchronization to the rhythm.
Topic Area: PERCEPTION & ACTION: Audition