Poster E114, Monday, March 27, 2:30 – 4:30 pm, Pacific Concourse
The effect of cue-evoked expectation on different pain sensations
Emily Hird1,3, Deborah Talmi1,2, Anthony Jones1,3, Wael El-Deredy1,3,4; 1University of Manchester, 2University of Princeton, 3Salford Royal NHS Foundation Trust, 4Valparaiso University
Pain perception is influenced by expectations of its intensity , and it is well established that this correlates with changes in neural pain processing. However, our environment has various sources of pain, and different pain sources are perceived through different nociceptive pathways. It is not known whether different pain types are influenced by expectation in the same way, or whether changing the sensory properties of pain influences the effect of expectation. We present the results of an ERP study comparing the modulation by cue-evoked expectation of electric pain and laser pain. Fourteen participants received laser and electric stimulation, signalled by a cue. Cues indicated the likely intensity of the upcoming pain. We measured Event-Related Potentials (ERPs) to medium pain stimulation after a cue signalling high or low pain. Subjective pain ratings and corresponding pain-evoked ERPs increased in amplitude after presentation of a high intensity cue, and reduced in intensity after presentation of a low intensity cue. Crucially, statistical analysis showed this modulation to be equal in response to both laser and electric pain. High pain cue elicited a greater anticipatory neural signal than low pain cue across pain types. We show that modulation of pain and anticipatory signalling by expectancy is not changed by pain sensation.
Topic Area: PERCEPTION & ACTION: Multisensory