Poster E86, Monday, March 27, 2:30 – 4:30 pm, Pacific Concourse
Reactivation of Emotional Context during Successful Recollection: A Partial Least Squares Analysis
Holly Bowen1, Elizabeth Kensinger1; 1Boston College
Episodic memory involves bringing back to mind details from encoding at the time of retrieval. One marker of this is neural reactivation. In the current fMRI study, participants (N =18) intentionally encoded neutral words paired with a positive, neutral or negative face or scene. They then completed a remember/know judgment for the neutral words; the emotional face or scene was not re-presented at retrieval. We examined retrieval-related activation associated with words previously encoded in a positive, neutral or negative context, using mean-centered Partial Least Squares (McIntosh et al., 2004), a multivariate technique optimal for identifying spatio-temporal whole-brain patterns. One analysis was run for words that had been encoded with faces, and a second analysis examined words that had been encoded with scenes. The first analysis yielded a significant latent variable (LV) showing a pattern of activation in lateral frontal regions and the ventral visual stream that correlated with recollection of words previously encoded with a negative face compared to a positive or neutral face. A second analysis revealed an LV pattern that differentiated activation correlated with successful recollection of words encoded with a negative scene compared to positive scene context. Again, negative context was associated with distributed activation in lateral frontal and anterior sensory regions, but positive context with more medial frontal and posterior sensory regions. These results add to the growing literature suggesting negative valence leads to more detailed, vivid memories and shed light on how a neutral trigger can reactivate sensory details from a previously experienced emotional event.
Topic Area: LONG-TERM MEMORY: Episodic