Integration of spatio-temporal dynamics in emotion-cognition interactions: A simultaneous fMRI-ERP investigation using the emotional odd-ball task
Matthew Moore1, Andrea Shafer2, Reyhaneh Bakhtiari3, Florin Dolcos1, Anthony Singhal3; 1University of Illinois at Urbana-Champaign, 2National Institute on Aging, 3University of Alberta
Despite a corpus of evidence highlighting that emotion-cognition interactions elicit specific patterns of response in brain regions associated with major brain networks, it is unclear how the mechanisms by which emotion interfaces with cognition are linked to spatial and temporal dynamics in the associated neural correlates. Thus, there is a need to capitalize on multi-modal brain imaging approaches in order to elucidate the underlying mechanisms of these phenomena. The present study used simultaneous functional magnetic resonance imaging (fMRI) and event-related potential (ERP) recordings, in conjunction with an emotional odd-ball task, in a sample of 22 healthy young adults. As expected, fMRI captured greater response in dorsal system brain regions (e.g., dorsolateral prefrontal cortex, lateral parietal cortex) to targets compared to emotional distracters, while ventral system regions (e.g., ventrolateral prefrontal cortex, occipitotemporal cortex) showed greater response to emotional distracters. ERP responses to targets were associated with a prominent P300, and responses to distracters were associated with late positive potentials that showed greater amplitude for emotional compared to neutral distracters. Furthermore, ERP-informed fMRI analyses showed that ERP amplitude to targets was associated with blood-oxygen-level dependent (BOLD) signal in regions showing enhanced response to targets, and ERP amplitude to emotional distracters was associated with BOLD signal in regions showing enhanced response to distracters. Together, these results identify convergence and complementarity between measures of brain activity spanning different spatial and temporal resolutions, which supports the feasibility of using multi-modal brain imaging approaches to clarify the neural mechanisms associated with emotion-cognition interactions.
Topic Area: EMOTION & SOCIAL: Emotion-cognition interactions