Poster A70, Saturday, March 25, 5:00 – 7:00 pm, Pacific Concourse
Examination of the relationship between resting state neural oscillations and lexical semantic retrieval in mild traumatic brain injury
Marissa DeCaro1, Amy Ramage1, Stephanie Barlow1, Daniel Seichepine2, Robert Ross1; 1University of New Hampshire, 2University of New Hampshire-Manchester
Mild traumatic brain injury (mTBI) is an impact to the head that causes neurological symptoms for any period of time. Language deficits observed following concussion appear to be due to disruptions in white matter integrity that changing neural communication. This study assessed oscillatory power, an index of neural communication recorded with EEG, to identify how resting-state network activity relates to lexical-semantic retrieval in young adults reporting between 2-5 concussion events who were at least 4 weeks post-concussion. Performance on the Boston Naming Test (BNT) was correlated with resting oscillatory power in the theta (4-8 Hz) and two gamma frequency bands, 30-50 (low gamma) and 70-90 Hz (high gamma). EEG data was recorded with a 64-channel ActiChamp system as participants sat in quiet wakefulness for four minutes with their eyes open. Four ROIs over posterior regions of the brain were defined. Multivariate regression was used to determine whether theta, low, or high gamma Hz bands recorded in our ROIs is predictive of performance on the BNT. Our preliminary results show that our model has an R2 = .743, suggesting performance on the BNT is predicted by theta and gamma oscillatory power over posterior brain regions during rest. These results may help to identify which oscillatory bands correlate with difficulty of word retrieval in mTBI.
Topic Area: LANGUAGE: Semantic