Poster E118, Monday, March 27, 2:30 – 4:30 pm, Pacific Concourse
Oscillatory brain correlates of the hypnotically-induced out-of-body experience
Abraham Goldstein1, Maor Zeev-Wolf1, Yair Dor-Ziderman1, Eitan G Abramowitz2; 1Bar-Ilan University, 2Hadassah Medical Center and Hebrew University
One of the most challenging questions regarding the nature and neural basis of consciousness concerns its being an embodied phenomenon, that is, feeling located within the body and viewing the world from that spatial perspective. Current theories in neurophysiology highlight the active role of multisensory and sensorimotor integration in supporting self-location and self-perspective, and propose the right temporal-parietal-junction (rTPJ) as a key area for such function. The theories are based mainly on findings from two experimental paradigms: manipulation of bottom-up multisensory information integration regarding one’s body location (full-body illusion), or direct and invasive manipulation disrupting brain activity at the TPJ. In this study we take a different approach by using hypnotic suggestion – a non-invasive top-down technique - to manipulate subjective experience of self-location. We tested 18 right-handed neurotypical participants and recorded their brain activity using magnetoencephalography (MEG) while hypnotically manipulating their subjective experience of self-location. Spectral analyses were conducted on recordings of spontaneous brain activity before and during induction of an out-of-body experience by a trained psychiatrist. The results indicate high correlations between power at alpha and high-gamma frequency-bands and the degree of perceived change in self-location. Regions exhibiting such correlations include temporal-occipital regions, the right TPJ, as well as frontal and midline regions. These findings are in line with an oscillatory-based predictive coding framework.
Topic Area: PERCEPTION & ACTION: Multisensory